Support Chemistry

Dr. Ashley McDonald

Assistant Professor

Specialty

Theoretical and Computational Chemistry

Education

B.S. Chemistry, Mississippi College 2004
Ph.D. Georgia Institute of Technology 2009
Post-doctoral School of Pharmacy, U of Maryland, Baltimore 2009-11

Office: Faculty Offices - Bldg 25 - 213

Phone: (805) 756-7536

E-Mail: armcdona@calpoly.edu

Research Interests

  • Using computational chemistry to study noncovalent interactions in complex biophysical systems, particularly nucleic acids
    • Studying the effects of pi stacking between bases in nucleic acids
    • Developing computational tools (computer programming) to examine the effects of geometry on pi stacking in nucleic acids
  • Computational analysis of naphthalquinoline geometries to understand their binding affinity and specificity for triplex DNA
  • Calculating interaction energies between DNA aptamers and ligands, to understand mechanisms for riboswitches and potential nucleic acid therapeutics
  • Broad interest in computational drug design

 

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